Collagen Biology by Gender & Ethnicity
CHAPTER 3 — BIOLOGICAL DIFFERENCES
Gender-Based Biological Differences
Female Skin
- thinner dermis
- more collagen loss during perimenopause
- oestrogen maintains collagen & hyaluronic acid
- faster decline post-menopause
- more prone to fine lines & crepey texture
Male Skin
- 25% thicker dermis
- denser collagen network
- slower collagen decline
- oilier surface → more inflammation risk
- more resistant to wrinkles but deeper when present
Transgender Women (MTF, on oestrogen/HRT)
- dermis thins gradually
- muscle volume reduces
- slower collagen turnover
- finer texture develops
- increased sensitivity
Transgender Men (FTM, on testosterone/HRT)
- skin thickens
- oil production increases
- higher acne/inflammation risk
- stronger collagen network develops
These differences impact:
- treatment energy
- depth selection
- session scheduling
- expected healing
- collagen response timeline
Ethnicity & Collagen Biology
Different ethnicities show different collagen behaviours.
Fitzpatrick I–III (lighter skin types):
- faster collagen thinning
- more UV damage
- higher wrinkle formation
- weaker elastin
Fitzpatrick IV–VI (darker skin types):
- denser collagen structure
- slower wrinkle development
- higher risk of PIH
- stronger elastin network
- thicker dermis
This impacts:
- treatment tolerance
- wavelength selection
- post-treatment recovery
- risk of pigmentation disturbance
The Art of Scientific Aesthetics
Frequently Asked Questions
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It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.
It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.
It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.
It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.
