Melanin Production — The Full Pathway

How Melanin Is Made — What Must Be Controlled to Lighten Safely

Melanin pathways, inflammation triggers, hormonal activation, vascular–pigment interaction, heat-based responses and genetic behaviour

HOW MELANIN IS PRODUCED — THE FULL PATHWAY

Your pigmentation begins inside the melanocyte, a highly intelligent cell located at the base of the epidermis.

THE MELANIN PRODUCTION SYSTEM

Every melanocyte contains:

  • melanosomes (pigment factories)
  • tyrosinase (the enzyme that begins pigment formation)
  • MITF (the master gene controlling pigment)
  • dendrites (branches that deliver pigment to surrounding skin cells)

Melanin formation steps:

  1. UV, heat, hormones or inflammation send a “danger” signal
  2. MITF activates
  3. Tyrosinase switches on
  4. Melanin begins forming inside the melanosome
  5. The melanocyte exports melanin into surrounding skin cells
  6. Pigment becomes visible on the surface

This is why treating pigmentation is extremely difficult:

you are dealing with a factory system, not a “spot of colour.”

THE 3 TYPES OF MELANIN — WHY YOUR COLOUR BEHAVES DIFFERENTLY

Humans produce two key pigments:

  1. EUMELANIN (brown)
  • protective
  • absorbs UV
  • stable
  • common in medium–deep skin
  1. PHEOMELANIN (yellow/red)
  • less protective
  • oxidises easily
  • more reactive in lighter skin
  • linked to inflammation + redness
  1. MIXED MELANIN
  • most common in facial pigmentation
  • leads to brown-red or brown-grey patterns
  • influenced by genetics, hormones and inflammation

Aeternitas technology targets different melanin types during treatment — making the results more stable.

The Art of Scientific Aesthetics

Frequently Asked Questions

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It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.

It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.

It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.

It is a long established fact that a read will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more or less.

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